Abstract : An original metal-free regio- and stereoselective intermolecular hydroamination of alkynes is described. Various (E)-enamines were obtained from arylacetylenes and aliphatic secondary amines in the presence of ethylene glycol as a solvent. The latter is assumed to play a major role in the mechanism through hydrogen bonding and proton exchange.
https://hal.umontpellier.fr/hal-02390470
Contributor : Odile Hennaut <>
Submitted on : Thursday, January 7, 2021 - 11:04:58 AM Last modification on : Tuesday, February 9, 2021 - 11:24:48 AM