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Diagnosis of Mycobacterium ulcerans infections in French Guiana

Abstract : THE SITUATION: Buruli's ulcer is a severe necrotic cutaneous infection due to Mycobacterium ulcerans. It is a major public health problem in developing countries. FROM A CLINICAL POINT OF VIEW: The early stage of the infection corresponds to a painless cutaneous nodule, whereas the late stage corresponds to ulceration with detachment of the edges. There is currently no other treatment than surgical excision combined with heat therapy. FROM A DIAGNOSTIC POINT OF VIEW: Three methods can be used: direct examination of swabs stained according to Ziehl-Neelsen's method, culture in specific medium at 32 degrees C and the polymerization chain reaction assay (PCR). The latter is the technique of choice.
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Submitted on : Monday, July 12, 2021 - 6:29:19 PM
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Ghislaine Prevot, L. Marsollier, B. Carbonelle, R. Pradinaud, P. Coupié, et al.. Diagnosis of Mycobacterium ulcerans infections in French Guiana. La Presse Médicale, Elsevier Masson, 2004, 33 (21), pp.1516. ⟨10.1016/s0755-4982(04)98974-9⟩. ⟨hal-03284761⟩



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