UG - Université de Guyane : EA3593 (Campus de Troubiran - BP 20792- 97337 Cayenne Cedex - Guyane - French Guiana)
Abstract : THE SITUATION: Buruli's ulcer is a severe necrotic cutaneous infection due to Mycobacterium ulcerans. It is a major public health problem in developing countries. FROM A CLINICAL POINT OF VIEW: The early stage of the infection corresponds to a painless cutaneous nodule, whereas the late stage corresponds to ulceration with detachment of the edges. There is currently no other treatment than surgical excision combined with heat therapy. FROM A DIAGNOSTIC POINT OF VIEW: Three methods can be used: direct examination of swabs stained according to Ziehl-Neelsen's method, culture in specific medium at 32 degrees C and the polymerization chain reaction assay (PCR). The latter is the technique of choice.
Ghislaine Prevot, L. Marsollier, B. Carbonelle, R. Pradinaud, P. Coupié, et al.. Diagnosis of Mycobacterium ulcerans infections in French Guiana. La Presse Médicale, Elsevier Masson, 2004, 33 (21), pp.1516. ⟨10.1016/s0755-4982(04)98974-9⟩. ⟨hal-03284761⟩